D.N.A. Cellular Anti-Aging Cream increases firmness of the skin while delivering powerful anti-wrinkle action by starfish extract (no starfish is harmed in the process of extraction). Clinically proven to reduce the number of depth of both deep and medium-deep wrinkles after a 28 day application. Includes Vitamin E, C, A, and Aloe Vera as anti-oxidants and sooth the skin.
This Anti-Aging Cream is a superb solution to regain a younger, glowing, and radiant appearance. It provides exceptional barrier and protection, and leaves the skin supple and bright, while promoting the natural cell regeneration process. It also prevents water from leaving the skin, and increases long-term cell health. This long-lasting cellular regeneration essence provides unprecedented radiance.
Starfish Extract’s Retinol-Like Action for Safe Anti-Aging Formulations
Starfish Extract’s Safe Retinol-Mimetic Action is the New and Unique Way to Attenuate Visible Signs of Skin Aging without Any Adverse Effects
Skin aging is a continuous and permanent process. Aging induces degradation of many skin properties and functions, with a gradual loss of barrier function, a slower turnover of epithelial cells as well as a decrease in the quality and functionality of the extracellular matrix.
Ecoceolomic Fluid Collection: Sustainable & Scalable for Private Label Products
- Harvesting of starfish in partnership with mussel fishermen;
- Transportation to mobile collecting facilities in seawater tanks;
- Non-harmful and soft coelomic fluid collecting, micro-filtering;
- Formulation of D.N.A. Starfish Extract;
- Reintroducing the starfish to their natural marine environment.
Key Benefits for Advanced Anti-Aging Skincare Formulations
Proven Efficacy
A cream containing 1.6% of D.N.A. Starfish Extract was applied twice daily (27 volunteers, aged 40 to 70), during 28 days. This clinical study has shown significant improvements in wrinkle depth, volume, elasticity, firmness, and moisturization.
The video below shows the first 24h of the recolonization process by normal human keratinocytes in culture, comparing the control cells (top) to cells treated with starfish coelomic fluid from D.N.A.’s Asteria vulgaris (bottom).
Starfish coelomic fluid treatment doubled the speed of keratinocyte recolonization of the injured area.
Starfish coelomic fluid treatment doubled the speed of keratinocyte recolonization of the injured area.
In a clinical study using a 1.6% D.N.A. Anti-Aging cream or a placebo, mean values of wrinkles depth, width and volume were calculated for each subject, before and after 28 days of application of the test product.
After only 28 days of application, D.N.A. induced a significant reduction in the depth and volume of 18% and 21%, respectively. This reduction was also significant compared with the placebo, at 12% and 15%.
After only 28 days of application, D.N.A. induced a significant reduction in the depth and volume of 18% and 21%, respectively. This reduction was also significant compared with the placebo, at 12% and 15%.
Starfish Extract In-Vitro Efficacy
Normal keratinocytes from a 49-year-old donor were placed in a culture medium until confluence. An artificial wound was created by performing a scratch in the cellular monolayer, leaving a clear space that keratinocytes can recolonize. Keratinocyte cultures were treated with growth media (Control), TGF-β (a known wound healing-promoting factor), and coelomic fluid from Asteria vulgaris starfish (final concentration 0.048%). Promotion of wound healing is seen as increased recolonization of the wounded area.
Pictures of the wounded area were taken at baseline (A), and after 24h of recolonization under the control (B), TGF-β (C), or coelomic fluid (D) treatments, showing a clear, positive regenerative impact of coelomic fluid on the wound healing process.
Recolonization under control conditions reached 60.5% after 24h, while use of TGF-β stimulated keratinocyte recolonization to reach 88.7%. The use of coelomic fluid promoted significantly stronger recolonization than control as well as TGF-β, with 96.4% of recolonization after 24h.
Ex-Vivo Efficacy Supporting Anti-Aging Performance
Analysis of skin layers’ morphology was conducted after 6 days of topical application of 1.6% D.N.A. Star fish Extract (or retinol cream) on skin explants from a 60-year-old female donor.
The effects show D.N.A. Star fish Extract helps stimulate thickening of the epidermis more than a comparable retinol cream, while provoking none of the side effects of retinol.
The effects show D.N.A. Star fish Extract helps stimulate thickening of the epidermis more than a comparable retinol cream, while provoking none of the side effects of retinol.
Collagen & GAG Synthesis to Support Skin Structure
Analysis of type III and IV collagen and glycosaminoglycan synthesis after 6 days of topical application of 1.6% D.N.A. Starfish Extract (or retinol cream) was performed on skin explants from a 60-year-old female donor.
Ingredients
Water, Aloe Vera concentrate, glycerin, tetrasodium
ethylenediaminetetraacetic acid tetrasodium salt, caprylic/capric triglyceride, isoeicosane, glyceryl stearate, Vitamin C Palmitate, cetyl alcohol, Vitamin E Acetate, starfish coelomic fluid, Algae Extract.
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